Author

K. S. Iyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. W. Schmidtke· 2 shared M. Petroll· 2 shared M. Rao· 2 shared V. D. Varner· 2 shared A. Badrinarayanan· 1 shared A. Chimthanawala· 1 shared A. Mowla· 1 shared A. Saxena· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

D. W. Schmidtke

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Treatment with both TGF-β1 and PDGF-BB disrupts the stiffness-dependent myofibroblast differentiation of corneal keratocytes

K. S. Iyer, D. P. Maruri, D. W. Schmidtke, M. Petroll, V. D. Varner

This study shows that treatment with both TGF-β1 and PDGF-BB disrupts stiffness-dependent myofibroblast differentiation of corneal keratocytes, decoupling molecular markers from contractile behavior.

bioRxiv · Feb 29, 2024 · PreprintBioengineering

Corneal keratocytes, fibroblasts, and myofibroblasts exhibit distinct transcriptional profiles in vitro

K. Poole, K. S. Iyer, D. W. Schmidtke, M. Petroll, V. D. Varner

This study identifies distinct transcriptional profiles of cultured corneal keratocytes, fibroblasts, and myofibroblasts, revealing genes and pathways involved in their differentiation and potential therapeutic targets.

bioRxiv · Feb 28, 2024 · PreprintBioengineering

Polymer-mediated oligonucleotide delivery enables construction of barcoded 3D cultures for spatial single-cell analysis

J. J. King, A. Mowla, J. A. Kretzmann, M. Norret, U. D. Kadolsky, M. Iqbal, A. Saxena, S. S. A. Mamsa, S. E. Amos, Y. S. Choi, B. F. Kennedy, K. S. Iyer, N. M. Smith, C. W. Evans

The paper introduces a method to create barcoded 3D cell cultures for spatial single-cell analysis using polymer-mediated oligonucleotide delivery and multiplex single-cell RNA sequencing.

bioRxiv · Nov 20, 2023 · PreprintBioengineering

Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis

K. S. Iyer, C. Prabhakara, S. Mayor, M. Rao

The paper shows how cells use compartmentalisation and multiple receptors to accurately infer their position during morphogenesis, using Drosophila wing disc development as a case study.

bioRxiv · Mar 30, 2022Biophysics

SMC protein RecN drives RecA filament translocation and remodelling for in vivo homology search

A. Chimthanawala, J. J. Parmar, S. Kumar, K. S. Iyer, M. Rao, A. Badrinarayanan

This study identifies RecN as essential for RecA filament translocation and remodelling during homology search in Caulobacter, revealing a novel search strategy involving directional movement and dynamic filament changes.

bioRxiv · Aug 16, 2021 · PreprintCell Biology