Author

J. A. Lopez-Guerrero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. Garcia-Garcia· 3 shared M. R. Hidalgo· 3 shared Z. Andreu· 3 shared B. Gomez-Cabanes· 2 shared I. Soler-Saez· 2 shared R. A. Hernandez-Ramirez· 2 shared A. Fernandez-Serra· 1 shared A. Kalluchi· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

F. Garcia-Garcia

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5 papers

Recent·Most cited

Meta-analysis of the melanoma miRNome identifies consensus signatures of progression and prognosis regulating metabolic plasticity and stress resistance

B. Gomez-Cabanes, H. Gomez-Martinez, C. Galiana-Rosello, Z. Andreu, A. Lopez-Cerdan, N. M. Eskow, J. A. Lopez-Guerrero, B. Dolader-Rabinad, R. A. Hernandez-Ramirez, I. Soler-Saez, M. R. Hidalgo, E. Hernando, F. Garcia-Garcia

This study identifies miRNA signatures associated with melanoma progression and prognosis by integrating transcriptomic data and analyzing miRNA-mRNA interactions.

bioRxiv · Oct 20, 2023 · PreprintCancer Biology

A comprehensive transcriptional signature in pancreatic ductal adenocarcinoma reveals new insights into the immune and desmoplastic microenvironment

I. Perez-Diez, Z. Andreu, M. R. Hidalgo, C. Perpina-Clerigues, L. Fantin, A. Fernandez-Serra, M. de la Iglesia-Vaya, J. A. Lopez-Guerrero, F. Garcia-Garcia

This study identifies 1153 dysregulated genes in PDAC that shape the desmoplastic stroma and immunosuppressive microenvironment, revealing two gene signatures and five novel prognostic immune genes.

bioRxiv · Mar 31, 2023 · PreprintCancer Biology

EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

S. Chakraborty, A. M. Bhat, I. Mushtaq, H. Luan, A. Kalluchi, S. Mirza, M. D. Storck, N. Chaturvedi, J. A. Lopez-Guerrero, A. Llombart-Bosch, I. Machado, K. Scotlandi, J. L. Meza, G. Ghosal, D. W. Coulter, , H. Band

This study shows EHD1 promotes Ewing sarcoma by regulating IGF-1R trafficking to the cell surface, which is essential for tumor growth and metastasis.

bioRxiv · Jan 15, 2023Cancer Biology

DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis

A. M. Trasierras-Fresco, Z. Andreu, B. Dolader Rabinad, M. R. Hidalgo, R. A. Hernandez-Ramirez, I. Soler-Saez, B. Gomez-Cabanes, A. Romero, J. A. Lopez-Guerrero, M. de la Iglesia Vaya, F. Garcia-Garcia

This study performs a meta-analysis of DNA methylation signatures in breast cancer, identifying common deregulation in immune system and cell cycle pathways across subtypes.

bioRxiv · Oct 15, 2022 · PreprintCancer Biology

Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma.

D. Hervas-Marin, F. Higgins, O. Sanmartin, J. A. Lopez-Guerrero, M. C. Bano, J. C. Igual, I. Quilis, J. Sandoval

This study identifies epigenetic features in high-risk cutaneous squamous cell carcinoma through genome-wide DNA methylation profiling and develops a prognostic model based on methylation signatures.

bioRxiv · Sep 20, 2019Cancer Biology