Author

K. Scotlandi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Pazzaglia· 2 shared A. C. De Luca· 1 shared A. Di Giannatale· 1 shared A. Kalluchi· 1 shared A. Llombart-Bosch· 1 shared A. M. Bhat· 1 shared B. C. Mohapatra· 1 shared C. Blanco· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

L. Pazzaglia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genomic and phenotypic stability of fusion-driven pediatric Ewing sarcoma cell lines

M. Kasan, J. Siebenlist, M. Sill, R. Oellinger, E. de Alava, D. Surdez, U. Dirksen, I. Oehme, K. Scotlandi, O. Delattre, M. Mueller-Nurasyid, R. Rad, K. Strauch, T. G. P. Gruenewald, F. Cidre-Aranaz

This study compares genomic and phenotypic stability of pediatric Ewing sarcoma cell lines to adult carcinoma cell lines over 12 months of culture.

bioRxiv · Nov 20, 2023 · PreprintCell Biology

Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis

T. Gonzalez-Munoz, A. Di Giannatale, S. Garcia-Silva, V. Santos, S. Sanchez-Redondo, C. Savini, O. Grana-Castro, C. Blanco, D. J. Pisapia, J. L. Peralto, C. Romagosa Perez-Portabella, R. Alaggio, M. S. Benassi, L. Pazzaglia, K. Scotlandi, , H. Peinado

This study identifies endoglin (ENG) as a biomarker and therapeutic target for MPNSTs, showing that targeting ENG with antibodies or combining it with MEK inhibitors reduces tumor growth and metastasis.

Clinical Cancer Research · Jul 11, 2023Peer-reviewedCancer Biology

EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

S. Chakraborty, A. M. Bhat, I. Mushtaq, H. Luan, A. Kalluchi, S. Mirza, M. D. Storck, N. Chaturvedi, J. A. Lopez-Guerrero, A. Llombart-Bosch, I. Machado, K. Scotlandi, J. L. Meza, G. Ghosal, D. W. Coulter, , H. Band

This study shows EHD1 promotes Ewing sarcoma by regulating IGF-1R trafficking to the cell surface, which is essential for tumor growth and metastasis.

bioRxiv · Jan 15, 2023Cancer Biology

Profilin 1 deficiency drives mitotic defects and impairs genome stability

F. Scotto di Carlo, S. Russo, F. Muyas, M. Mangini, L. Pazzaglia, F. Biamonte, A. C. De Luca, K. Scotlandi, I. Cortes-Ciriano, F. Gianfrancesco

This study shows that Profilin 1 deficiency causes mitotic defects and genome instability in cancer cells.

bioRxiv · Feb 1, 2022Cell Biology