Author

H.-H. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Silva· 1 shared A.-P. Cheng· 1 shared B. Tomita· 1 shared C.-C. Lin· 1 shared C.-H. CHEN· 1 shared C.-H. Ho· 1 shared C.-K. Tang· 1 shared C.-T. Pan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. A. Silva

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanical transmission of Dengue Virus by Aedes aegypti may influence disease transmission dynamics during outbreaks

H.-H. Li, M. P. Su, S.-C. Wu, H.-H. Tsou, M.-C. Chang, Y.-C. Cheng, K.-N. Tsai, H.-W. Wang, G.-H. Chen, C.-K. Tang, P.-J. Chung, W.-T. Tsai, L.-R. Huang, Y. A. Yueh, H.-W. Chen, , C.-H. CHEN

This study shows that Aedes aegypti mosquitoes can mechanically transmit Dengue Virus to mice immediately after biting infected mice, impacting outbreak dynamics and suggesting implications for vector control.

bioRxiv · Mar 7, 2023 · PreprintMicrobiology

The evolution and structure of snake venom phosphodiesterase (svPDE) highlight its importance in venom actions

C.-T. Pan, C.-C. Lin, I.-J. Lin, K.-Y. Chien, Y.-S. Lin, H.-H. Chang, W.-G. Wu

This study investigates the evolution and structure of snake venom phosphodiesterase (svPDE), showing it evolved from the ENPP3 gene and plays a key role in venom function through purinergic signaling and insulin transduction.

bioRxiv · Nov 24, 2022Evolutionary Biology

Plant A20/AN1 proteins coordinate different immune responses including RNAi pathway for antiviral immunity

L. Chang, H.-H. Chang, Y.-S. Chiu, J.-C. Chang, D.-W. Hsu, Y. Tzean, A.-P. Cheng, H.-C. Lu, H.-H. Yeh

This study identifies Pha21, an orchid A20/AN1 protein, as a key regulator of SA-mediated antiviral immunity, showing its role in RNAi pathway genes DCL4 and AGO1 expression, distinct from Pha13.

bioRxiv · May 27, 2019 · PreprintPlant Biology

Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis

H.-H. Chang, C.-H. Ho, B. Tomita, A. A. Silva, J. A. Sparks, E. W. Karlson, D. A. Rao, Y. C. Lee, I.-C. Ho

The paper identifies a PTPN22 gene signature in RA patients that can be reversed by targeted therapies and correlates with clinical response.

bioRxiv · Mar 24, 2019Immunology