Author

J. A. Tuszynski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 7

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

D. L. Sekulic· 2 shared M. Cifra· 2 shared A. N. Nguyen· 1 shared A. T. Ayoub· 1 shared B. M. Sataric· 1 shared C. Simon· 1 shared D. Havelka· 1 shared E. A. Rietman· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBiophysics

D. L. Sekulic

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Author profile →

7 papers

Recent·Most cited

Modeling the structure of the frameshift stimulatory pseudoknot in SARS-CoV-2 reveals multiple possible conformers

S. I. Omar, M. Zhao, R. V. Sekar, S. A. Moghadam, J. A. Tuszynski, M. T. Woodside

The paper models the structure of the SARS-CoV-2 frameshift stimulatory pseudoknot using computational methods and simulations, identifying multiple possible conformations.

bioRxiv · Jun 8, 2020Biophysics

Multifractal Nature of Microtubule Dynamic Instability Process

J. A. Tuszynski, V. Rezania, F. C. Sudirga

This paper uses multifractal analysis to show that microtubule length time series exhibit true multifractal properties, distinguishing experimental data from simulated data.

bioRxiv · May 28, 2020Biophysics

How signals of calcium ions initiate the beats of cilia and flagella

J. A. Tuszynski, M. Sataric, T. Nemes, D. L. Sekulic

This paper investigates how calcium ions initiate and synchronize ciliary and flagellar beating through their interaction with microtubules and tubulin modifications.

bioRxiv · Mar 23, 2019Biophysics

Tubulin as a sensitive target of nanosecond-scale intense electric field: quantitative insights from molecular dynamics simulations

P. Marracino, D. Havelka, J. Prusa, M. Liberti, J. A. Tuszynski, A. T. Ayoub, F. Apollonio, M. Cifra

This study uses molecular dynamics simulations to show that intense nanosecond electric fields can alter β-tubulin conformations and drug binding sites, suggesting potential for modulating microtubule dynamics.

bioRxiv · Jan 29, 2019 · PreprintBiophysics

Gibbs Free Energy of Protein-Protein Interactions Correlates with ATP Production in Cancer Cells

S. M. Golas, A. N. Nguyen, E. A. Rietman, J. A. Tuszynski

The paper finds an inverse correlation between Gibbs free energy of protein-protein interaction networks and oxidative phosphorylation in cancer cells, linking metabolic shifts to signaling pathway dysregulation.

bioRxiv · Dec 16, 2018Biophysics

Nonlinear calcium ion waves along actin filaments control active hair-bundle motility

J. A. Tuszynski, B. M. Sataric, M. V. Sataric, D. L. Sekulic, S. Zdravkovic

This paper presents a biophysical model showing how calcium ion waves along actin filaments control hair-bundle motility through nonlinear dynamics and myosin motor tuning.

bioRxiv · Mar 30, 2018Biophysics

Monitoring Microtubule Mechanical Vibrations via Optomechanical Coupling

S. Barzanjeh, V. Salari, J. A. Tuszynski, M. Cifra, C. Simon

This paper proposes a method to monitor microtubule mechanical vibrations using optomechanical coupling to study their dynamic properties for potential cancer treatment applications.

bioRxiv · Jan 2, 2017Biophysics