Author

J. Afzal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kshitiz· 2 shared W. Du· 2 shared Y. Liu· 2 shared Y. Suhail· 2 shared A. Atiq· 1 shared A. Hamidzadeh· 1 shared A. Levchenko· 1 shared C. Liang· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Kshitiz

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Author profile →

3 papers

Recent·Most cited

Stable and Oscillatory Hypoxia Differentially Regulate Invasibility of Breast Cancer Associated Fibroblasts

W. Du, Y. Liu, J. Afzal, S. Liu, Y. Suhail, Kshitiz

This study shows that stable and oscillatory hypoxia differentially regulate the invasiveness of breast cancer-associated fibroblasts through distinct molecular and mechanical mechanisms.

bioRxiv · Mar 26, 2024Cancer Biology

Oscillatory Hypoxia Induced Unfolded Protein Folding Response Gene Expression Predicts Low Survival in Human Breast Cancer Patients

Y. Suhail, Y. Liu, W. Du, J. Afzal, A. Atiq, P. Vera-Licona, E. Agmon, Kshitiz

The paper shows oscillatory hypoxia induces a unique gene expression signature in breast cancer linked to poor survival.

bioRxiv · Jan 25, 2024 · PreprintCancer Biology

The Evolution of Placental Invasion and Cancer Metastasis are Causally Linked

K. Gupta, J. Afzal, J. D. Maziarz, A. Hamidzadeh, C. Liang, E. M. Erkenbrack, H. Nam, J.-D. Haeger, C. Pfarrer, T. Hoang, T. Ott, T. Spencer, M. Pavlicev, D. Antczak, A. Levchenko, G. P. Wagner

The paper links placental invasion and cancer metastasis by showing that human stromal cells are more permissive to invasion than bovine cells, supporting the Evolved Levels of Invasibility hypothesis.

bioRxiv · Jan 23, 2019Cancer Biology