Author

J. Amason

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Proia· 1 shared C. Bowes Rickman· 1 shared C. Farrell· 1 shared C. Haass· 1 shared C. Thomas· 1 shared C. Yu· 1 shared D. Duveau· 1 shared D. Roberts· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. D. Proia

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2 papers

Recent·Most cited

Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions

C. Yu, E. M. Lad, R. Mathew, S. Littleton, Y. Chen, K. Schlepckow, S. Degan, L. Chew, J. Amason, J. Kalnitsky, C. Bowes Rickman, A. D. Proia, M. Colonna, C. Haass, D. Saban

The paper identifies a common neuroprotective response of microglia at retinal atrophy sites in mice and humans, mediated by galectin-3 and Trem2 interactions.

bioRxiv · Jul 19, 2023Immunology

A Homogeneous SIRPα-CD47 Cell-Based, Ligand-Binding Assay: Utility for Small Molecule Drug Development in Immuno-oncology.

T. Burgess, J. Amason, J. Rubin, D. Duveau, L. Lamy, D. Roberts, C. Farrell, J. Inglese, C. Thomas, T. W. Miller

This paper develops a cell-based ligand-binding assay to identify small molecule inhibitors of the SIRP-CD47 interaction for immuno-oncology drug development.

bioRxiv · Dec 5, 2019Immunology