J. Rubin

Stronger bat predation and weaker environmental constraints predict longer moth tails

The paper evaluates the evolutionary balance between bat predation pressure and environmental constraints on moth tail length using phylogenetic and ecological data.

Data driven and cell specific determination of nuclei-associated actin structure

The paper introduces a machine learning method to quantify and reconstruct nuclei-associated F-actin in mesenchymal stem cells, revealing structural changes upon LINC complex disruption.

Depletion of Sun1/2 induces heterochromatin accrual in mesenchymal stem cells during adipogenesis

The paper compares the effects of Sun1/2 depletion and dnKASH on adipogenesis in MSCs, finding that dnKASH accelerates adipogenesis while Sun1/2 depletion increases heterochromatin on adipogenic genes.

Ex Vivo and In Vivo CD46 Receptor Utilization by Species D Human Adenovirus Serotype 26 (HAdV26)

This paper investigates the CD46 receptor utilization by Ad26 in vitro and in vivo, showing its role in infection and safety, but not all routes of administration.

Mechanically induced nuclear shuttling of β-catenin requires co-transfer of actin

This study shows dynamic mechanical strain induces nuclear translocation of β-catenin via actin transport, while static strain promotes YAP1 nuclear entry, highlighting distinct mechanoresponses.

Comparison of Mucosal and Intramuscular Immunization against SARS-CoV-2 with Replication-Defective and Replicating Single-cycle Adenovirus Vaccines

This study compares mucosal and intramuscular immunization with replication-defective and replicating single-cycle adenovirus vaccines against SARS-CoV-2, showing that replicating vaccines generate stronger antibody responses.

Lamin A/C functions independently from mechanical signaling during adipogenesis

This study shows that Lamin A/C is essential for adipogenesis but not required for mechanical signaling during MSC differentiation.

A Homogeneous SIRPα-CD47 Cell-Based, Ligand-Binding Assay: Utility for Small Molecule Drug Development in Immuno-oncology.

This paper develops a cell-based ligand-binding assay to identify small molecule inhibitors of the SIRP-CD47 interaction for immuno-oncology drug development.

Prevalence of beta-lactam drug-resistance genes in commensal Escherichia coli contaminating ready-to-eat lettuce

This study found that a significant proportion of E. coli isolates from ready-to-eat lettuce in Northern California carry beta-lactam resistance genes, posing a potential risk for human infections.

Prevalence of antimicrobial resistance genes and integrons in commensal Gram-negative bacteria in a college community

This study identifies antimicrobial resistance genes and integrons in commensal Gram-negative bacteria from a healthy college population and links them to uropathogenic E. coli causing urinary tract infections.

Corticostriatal synaptic weight evolution in a two-alternative forced choice task

This study simulates corticostriatal synaptic weight evolution using a dopamine-driven plasticity rule in a two-alternative forced choice task, showing direct pathway weights adapt to reward outcomes.