An mTOR Inhibitor Discovery System Using Drug-Sensitized Yeast
Anna K. Breen, Sarah Ann Thomas, David Beckett, Matthew Agsalud, Graham Gingras, J. Andrew Williams, Brian M. Wasko
This paper develops a yeast-based system to identify TOR inhibitors, demonstrating high sensitivity and effectiveness in detecting known and novel compounds.
bioRxiv · Jan 3, 2025 · PreprintMolecular Biology