Author

J. Annes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

A. S. Y. Poon· 1 shared B. L. Roth· 1 shared D. G. Chopra· 1 shared E. A. Thomson· 1 shared G. Ku· 1 shared H. Xu· 1 shared K. Shariati· 1 shared N. Yiv· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. S. Y. Poon

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2 papers

Recent·Most cited

An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant

R. A. Lee, D. G. Chopra, V. Nguyen, X.-P. Huang, Y. Zhang, K. Shariati, N. Yiv, R. Schugar, J. Annes, B. L. Roth, G. Ku

The paper identifies the serotonin 1F receptor as a negative regulator of human beta cell survival during transplant and demonstrates a small molecule antagonist that improves glycemia in islet transplants.

bioRxiv · May 1, 2024 · PreprintCell Biology

β-Cells as a Cell Factory for On-Demand Recombinant Protein Dosing: Harnessing the Neuroendocrine Cell Secretory Pathway for Controlled Release

A. S. Y. Poon, J. Annes, E. A. Thomson, R. A. Lal, H. Xu, S. Lee

This paper develops a β-cell-based platform for on-demand recombinant protein delivery by modifying the endogenous insulin processing pathway to produce and release therapeutic peptides like GLP-1 or glucagon.

bioRxiv · Jan 20, 2024 · PreprintBioengineering