J. Ardanuy

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression

This study shows that SARS-CoV-2 ORF8 protein modulates lung inflammation and disease severity in mice by affecting macrophage infiltration and function.

CNP blocks mitochondrial depolarization and inhibits SARS-CoV-2 replication in vitro and in vivo

This paper identifies CNP as a novel antiviral target that inhibits SARS-CoV-2 replication by blocking mitochondrial depolarization and mPTP activation in vitro and in vivo.