Author

L. Baracco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Dillen· 3 shared M. Frieman· 3 shared L. Taylor· 2 shared M. McGrath· 2 shared N. Assad-Garcia· 2 shared S. Vashee· 2 shared Y. Xue· 2 shared G. Smith· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

C. Dillen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression

M. Frieman, M. E. McGrath, Y. Xue, L. Taylor, C. Dillen, J. Ardanuy, N. Gonzalez-Juarbe, L. Baracco, R. Kim, R. Hart, N. Assad-Garcia, S. Vashee

This study shows that SARS-CoV-2 ORF8 protein modulates lung inflammation and disease severity in mice by affecting macrophage infiltration and function.

bioRxiv · Sep 8, 2023Microbiology

Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2

R. Johnson, J. Ardunay, H. Hammond, J. Logue, L. Jackson, L. Baracco, M. McGrath, C. Dillen, N. Patel, G. Smith, M. Frieman

This study shows that obesity and diabetes increase SARS-CoV-2 mortality and reduce vaccine efficacy in mice, with neutrophil depletion improving outcomes.

bioRxiv · Oct 15, 2022Microbiology

SARS-CoV-2 Variant Spike and accessory gene mutations alter pathogenesis

M. McGrath, Y. Xue, C. Dillen, L. Oldfield, N. Assad-Garcia, J. Zaveri, N. Singh, L. Baracco, L. Taylor, S. Vashee, M. Frieman

This study investigates how non-Spike mutations in SARS-CoV-2 variants affect pathogenesis and transmission, revealing that accessory gene mutations can lead to attenuating phenotypes.

bioRxiv · May 31, 2022Microbiology