Author

J. Asthana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

T. Surrey· 2 shared W. M. Lim· 2 shared A. Costa· 1 shared D. Normanno· 1 shared F. Martino· 1 shared J. Gannon· 1 shared J. Locke· 1 shared J. Roostalu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

T. Surrey

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2 papers

Recent·Most cited

Gradual Compaction of the Central Spindle Decreases its Dynamicity as Revealed in PRC1 and EB1 Gene-Edited Human Cells

J. Asthana, N. I. Cade, D. Normanno, W. M. Lim, T. Surrey

The paper quantifies dynamic changes in the central spindle during mitosis in human cells using gene-edited fluorescent markers and finds it becomes more stable as it compacts.

bioRxiv · Jul 9, 2020 · PreprintCell Biology

Microtubule Nucleation by Single Human γTuRC in a Partly Open Asymmetric Conformation

T. Consolati, J. Locke, J. Roostalu, J. Asthana, W. M. Lim, J. Gannon, F. Martino, A. Costa, T. Surrey

This study characterizes the nucleation properties of human γTuRC using TIRF microscopy and cryo-EM, revealing an asymmetric conformation that explains its kinetic inhibition of microtubule nucleation.

bioRxiv · Nov 23, 2019 · PreprintBiochemistry