Author

J. Locke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Plant Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Arabidopsis· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Costa· 1 shared A. G. Freud· 1 shared A. Pena· 1 shared B. Knott· 1 shared C. A. Moores· 1 shared C. C. Hoogenraad· 1 shared D. Epstein· 1 shared E. Chan· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Costa

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development

M. E. Greene, R. Asiimwe, E. Wright, M. Bell, D. Epstein, S. D. Yates, B. Knott, S. Fry, S. Clevenger, J. Locke, S. C. Little, H. Richter, A. G. Freud, P. M. Porrett

This study identifies sequential transcriptional programs of tissue residency driving human uterine NK cell development through single-cell analyses.

bioRxiv · Feb 29, 2024 · PreprintImmunology

The mechanism of selective kinesin inhibition by kinesin binding protein.

J. Atherton, J. J. A. Hummel, N. Olieric, J. Locke, A. Pena, S. S. Rosenfeld, M. O. Steinmetz, C. C. Hoogenraad, C. A. Moores

This study identifies how kinesin binding protein selectively inhibits specific kinesins by structurally distorting their motor domains and blocking microtubule attachment.

bioRxiv · Jul 17, 2020 · PreprintBiochemistry

An ABA-GA bistable switch can account for natural variation in the variability of Arabidopsis seed germination time

K. Abley, P. Formosa-Jordan, H. Tavares, E. Chan, O. Leyser, J. Locke

The paper examines phenotypic variability in Arabidopsis seed germination time, identifies two loci involved, and models a GA/ABA bistable switch that amplifies variability and contributes to bet hedging.

bioRxiv · Jun 5, 2020Plant Biology

Microtubule Nucleation by Single Human γTuRC in a Partly Open Asymmetric Conformation

T. Consolati, J. Locke, J. Roostalu, J. Asthana, W. M. Lim, J. Gannon, F. Martino, A. Costa, T. Surrey

This study characterizes the nucleation properties of human γTuRC using TIRF microscopy and cryo-EM, revealing an asymmetric conformation that explains its kinetic inhibition of microtubule nucleation.

bioRxiv · Nov 23, 2019 · PreprintBiochemistry

Widespread inter-individual gene expression variability in Arabidopsis thaliana

S. Cortijo, Z. Aydin, S. Ahnert, J. Locke

This study identifies widespread gene expression variability among Arabidopsis thaliana plants under identical conditions and links it to environmental response genes and regulatory factors.

bioRxiv · Jun 19, 2018Plant Biology