Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness
S. L. P. Scroggs, J. T. Gass, R. Chinnasamy, S. G. Widen, S. R. Azar, S. L. Rossi, J. B. Arterburn, N. Vasilakis, K. A. Hanley
This study investigates resistance to fluoroquinolones in dengue virus serotype 4 and finds that resistance mutations affect viral fitness and binding/entry mechanisms.
bioRxiv · May 11, 2020Evolutionary Biology