Author

K. A. Hanley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Ecology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 3 Assay:bulk RNA-seq· 2 Research Focus:ecology & biodiversity· 2 Organism:human· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

B. M. Althouse· 3 shared N. Vasilakis· 3 shared S. L. Rossi· 3 shared S. R. Azar· 3 shared J. B. Arterburn· 2 shared R. Chinnasamy· 2 shared S. L. P. Scroggs· 2 shared W. Yu· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersEcology

B. M. Althouse

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Immunologically mediated trade-offs shaping transmission of sylvatic dengue and Zika viruses in native and novel non-human primate hosts

K. A. Hanley, H. Cecilia, S. R. Azar, B. Moehn, W. Yu, R. Yun, B. M. Althouse, N. Vasilakis, S. L. Rossi

This study investigates immunological trade-offs in non-human primate hosts for dengue and Zika viruses, finding that higher viral replication correlates with increased transmission but reduced antibody response.

bioRxiv · Jun 30, 2023 · PreprintMicrobiology

Ecological drivers of sustained enzootic yellow fever virus transmission in Brazil, 2017-2021

N. I. O. Silva, G. F. Albery, M. S. Arruda, G. F. O. Garcia, T. A. Costa, E. M. Mello, G. D. Moreira, E. V. Reis, S. A. Silva, M. C. Silva, M. G. Almeida, D. Becker, C. J. Carlson, N. Vasilakis, K. A. Hanley, B. P. Drumond

The paper investigates the ecological drivers of sustained yellow fever virus (YFV) transmission in Minas Gerais, Brazil, 2017-2021, finding higher infection and intensity in rural areas and warm/rainy seasons.

bioRxiv · Oct 19, 2022 · PreprintMicrobiology

Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness

S. L. P. Scroggs, J. T. Gass, R. Chinnasamy, S. G. Widen, S. R. Azar, S. L. Rossi, J. B. Arterburn, N. Vasilakis, K. A. Hanley

This study investigates resistance to fluoroquinolones in dengue virus serotype 4 and finds that resistance mutations affect viral fitness and binding/entry mechanisms.

bioRxiv · May 11, 2020Evolutionary Biology

Ecological processes underlying the emergence of novel enzootic cycles--arboviruses in the neotropics as a case study

S. Guth, K. A. Hanley, B. M. Althouse, M. Boots

This paper examines ecological processes that enable zoonotic pathogens to establish novel enzootic cycles, using arboviruses in the neotropics as a case study.

bioRxiv · Apr 24, 2020Ecology

Old drugs with new tricks: Efficacy of fluoroquinolones to suppress replication of flaviviruses

S. L. P. Scroggs, C. C. Andrade, R. Chinnasamy, S. R. Azar, E. E. Schirtzinger, E. I. Garcia, J. B. Arterburn, K. A. Hanley, S. L. Rossi

This study shows fluoroquinolones like enoxacin inhibit flavivirus replication in human cells and reduce ZIKV titer in mouse testes.

bioRxiv · Mar 30, 2020Microbiology

Wolbachia pipientis occurs in Aedes aegypti populations in New Mexico and Florida, USA

A. Kulkarni, W. Yu, J. Jiang, C. Sanchez, A. K. Karna, K. J. L. Martinez, K. A. Hanley, M. Buenemann, I. A. Hansen, R.-d. Xue, P. Ettestad, S. Melman, D. Duguma, M. Debboun, J. Xu

The study detects Wolbachia in wild Ae. aegypti mosquitoes from New Mexico and Florida, but not in Texas, and identifies the wAlbB strain.

bioRxiv · Mar 9, 2019Ecology

Schlafen 11 Restricts Flavivirus Replication

F. Valdez, J. Salvador, P. M. Palermo, J. E. Mohl, K. A. Hanley, D. Watts, M. Llano

This study shows that Slfn11 restricts flavivirus replication by impairing viral fitness, but not other steps of the viral life cycle.

bioRxiv · Oct 3, 2018Microbiology

Role of monkeys in the sylvatic cycle of chikungunya virus in Senegal

B. M. Althouse, M. Guerbois, D. A. T. Cummings, O. Diop, O. Faye, A. Faye, D. Diallo, B. D. Sadio, A. Sow, O. Faye, A. A. Sall, M. Diallo, B. Benefit, E. Simmons, D. M. Watts, , K. A. Hanley

The paper investigates the role of monkeys in the sylvatic cycle of chikungunya virus in Senegal using serosurveillance and mathematical modeling, finding that monkeys act as amplification hosts rather than reservoir hosts.

bioRxiv · Oct 13, 2017Ecology