A tropane-based ibogaine analog rescues folding-deficient SERT and DAT
S. Bhat, D. A. Guthrie, A. Kasture, A. El-Kasaby, J. Cao, A. Bonifazi, T. Ku, T. Ku, J. B. Giancola, T. Hummel, M. Freissmuth, A. H. Newman
The paper identifies a tropane-based ibogaine analog that rescues folding-deficient SERT and DAT mutants in vitro and in vivo.
bioRxiv · Jul 14, 2020Pharmacology & Toxicology