Author

J. B. Helms

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. R. Molenaar· 2 shared T. A. Wassenaar· 2 shared A. B. Vaandrager· 1 shared A. Chorlay· 1 shared A. Jeucken· 1 shared A. R. Thiam· 1 shared A. Toulmay· 1 shared C. H. A. van de Lest· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

M. R. Molenaar

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2 papers

Recent·Most cited

Lecithin:Retinol Acyl Transferase (LRAT) inducesthe formation of lipid droplets

M. R. Molenaar, T. A. Wassenaar, K. K. Yadav, A. Toulmay, M. C. Mari, L. Caillon, A. Chorlay, M. W. Haaker, R. W. Wubbolts, M. Houweling, A. B. Vaandrager, F. Reggiori, A. R. Thiam, W. A. Prinz, J. B. Helms

This study shows that LRAT produces retinyl esters in yeast, leading to lipid droplet formation, which is morphologically similar to wild-type droplets and confirmed by in silico and in vitro experiments.

bioRxiv · Aug 14, 2019Biochemistry

LION/web: a web-based ontology enrichment tool for lipidomic data analysis

M. R. Molenaar, A. Jeucken, T. A. Wassenaar, C. H. A. van de Lest, J. F. Brouwers, J. B. Helms

LION/web is a web-based tool that uses a lipid ontology to identify lipid-associated terms in lipidomic data, validated using macrophage and CHO cell datasets.

bioRxiv · Oct 7, 2018Biochemistry