Author

J. F. Brouwers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. G. M. Tielens· 2 shared J. J. van Hellemond· 2 shared A. I. de Kroon· 1 shared A. Jeucken· 1 shared A. S. Bierhuizen· 1 shared C. H. A. van de Lest· 1 shared C. H. De Smet· 1 shared C. S. Ejsing· 1 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

A. G. M. Tielens

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Author profile →

4 papers

Recent·Most cited

Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids

M. F. Renne, X. Bao, M. W. Hokken, A. S. Bierhuizen, M. Hermansson, T. Ewing, X. Ma, R. C. Cox, J. F. Brouwers, C. H. De Smet, C. S. Ejsing, A. I. de Kroon

The paper investigates mitochondrial lipid import in yeast, showing that di-unsaturated phosphatidylserine is preferentially imported for conversion to phosphatidylethanolamine, with ERMES and Vps39p facilitating this process.

bioRxiv · Jun 8, 2020Biochemistry

Schistosoma mansoni does not and cannot oxidize fatty acids, but these are used for biosynthetic purposes instead

M. L. Bexkens, M. M. Mebius, M. Houweling, J. F. Brouwers, A. G. M. Tielens, J. J. van Hellemond

This study shows that Schistosoma mansoni does not oxidize fatty acids but uses them for biosynthesis, which is critical for egg production and miracidium development.

bioRxiv · Nov 6, 2018Biochemistry

LION/web: a web-based ontology enrichment tool for lipidomic data analysis

M. R. Molenaar, A. Jeucken, T. A. Wassenaar, C. H. A. van de Lest, J. F. Brouwers, J. B. Helms

LION/web is a web-based tool that uses a lipid ontology to identify lipid-associated terms in lipidomic data, validated using macrophage and CHO cell datasets.

bioRxiv · Oct 7, 2018Biochemistry

Lipids are the preferred substrate of the protist Naegleria gruberi, relative of a human brain pathogen

M. Bexkens, V. Zimorski, M. J. Sarink, H. Wienk, J. F. Brouwers, J. F. De Jonckheere, W. F. Martin, F. R. Opperdoes, J. J. van Hellemond, A. G. M. Tielens

This study shows that Naegleria gruberi relies on lipid oxidation for growth and energy metabolism, unlike glucose or amino acids, and suggests similar metabolism in its pathogenic relative N. fowleri.

bioRxiv · Jul 24, 2018Biochemistry