Author

J. B. Shrager

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. J. Giaccia· 2 shared G. Bouchard· 2 shared S. K. Plevritis· 2 shared W. Zhang· 2 shared A. Bermudez· 1 shared A. Bhattacharya· 1 shared C. Kuo· 1 shared C. R. Bertozzi· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

A. J. Giaccia

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2 papers

Recent·Most cited

The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and lung cancer specimens

G. Bouchard, W. Zhang, I. Li, I. Ilerten, J. B. Shrager, A. Bhattacharya, Y. Li, W. Trope, M. G. Osawa, C. Kuo, L. Tian, A. J. Giaccia, S. K. Plevritis

The paper introduces the colocatome, a spatial-omic framework, to compare microenvironment features between tumour-stroma assembloids and lung cancer specimens, finding that fibroblasts protect cancer cells from treatment by reorganizing cytoarchitecture.

bioRxiv · Sep 11, 2023 · PreprintBioengineering

Multi-Omics Analysis of Fibroblasts from the Invasive Tumor Edge Reveals that Tumor-Stroma Crosstalk Induces O-glycosylation of the CDK4-pRB Axis

G. Bouchard, F. J. G. Marques, L. G. Karacosta, W. Zhang, A. Bermudez, N. M. Riley, L. C. Mehl, J. A. Benson, J. B. Shrager, C. R. Bertozzi, S. Pitteri, A. J. Giaccia, S. K. Plevritis

The paper analyzes multi-omics data from fibroblasts at the tumor edge and core to show O-glycosylation of the CDK4-pRB axis is induced by tumor-stroma crosstalk.

bioRxiv · May 28, 2021 · PreprintCancer Biology