Author

S. K. Plevritis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. J. Giaccia· 2 shared G. Bouchard· 2 shared J. B. Shrager· 2 shared W. Zhang· 2 shared A. Bermudez· 1 shared A. Bhattacharya· 1 shared A. Ribas· 1 shared A. Wang· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. J. Giaccia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level

C. Y. Yeh, K. Aguirre, O. Laveroni, S. Kim, A. Wang, B. Liang, X. Zhang, L. M. Han, R. Valbuena, S. K. Plevritis, M. C. Bassik, M. P. Snyder, B. E. Howitt, L. Jerby

This study maps ovarian cancer spatial organization and identifies immune evasion drivers through single-cell spatial transcriptomics and CRISPR screens.

bioRxiv · Oct 16, 2023Cancer Biology

The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and lung cancer specimens

G. Bouchard, W. Zhang, I. Li, I. Ilerten, J. B. Shrager, A. Bhattacharya, Y. Li, W. Trope, M. G. Osawa, C. Kuo, L. Tian, A. J. Giaccia, S. K. Plevritis

The paper introduces the colocatome, a spatial-omic framework, to compare microenvironment features between tumour-stroma assembloids and lung cancer specimens, finding that fibroblasts protect cancer cells from treatment by reorganizing cytoarchitecture.

bioRxiv · Sep 11, 2023 · PreprintBioengineering

Multi-Omics Analysis of Fibroblasts from the Invasive Tumor Edge Reveals that Tumor-Stroma Crosstalk Induces O-glycosylation of the CDK4-pRB Axis

G. Bouchard, F. J. G. Marques, L. G. Karacosta, W. Zhang, A. Bermudez, N. M. Riley, L. C. Mehl, J. A. Benson, J. B. Shrager, C. R. Bertozzi, S. Pitteri, A. J. Giaccia, S. K. Plevritis

The paper analyzes multi-omics data from fibroblasts at the tumor edge and core to show O-glycosylation of the CDK4-pRB axis is induced by tumor-stroma crosstalk.

bioRxiv · May 28, 2021 · PreprintCancer Biology

Trajectories from Snapshots: Integrated proteomic and metabolic single-cell assays reveal multiple independent adaptive responses to drug tolerance in a BRAF-mutant melanoma cell line

Y. Su, G. Li, M. E. Ko, H. Cheng, R. Zhu, M. Xue, J. Wang, J. W. Lee, L. Frankiw, A. Xu, S. Wong, L. Robert, K. Takata, S. Huang, A. Ribas, , J. R. Heath

The paper uses integrated proteomic and metabolic single-cell assays to identify two distinct adaptive pathways in BRAF-mutant melanoma cells during drug treatment.

bioRxiv · Sep 12, 2019 · PreprintBioengineering