Author

J. Bader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:multiple species· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

P. C. Karakousis· 3 shared W. M. Matern· 3 shared C. Danchik· 2 shared A. Srivastava· 1 shared B. M. Qureshi· 1 shared E. Montanari· 1 shared F. Brigger· 1 shared G. Patel· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

P. C. Karakousis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loading of extracellular vesicles with nucleic acids via hybridization with sponge-like lipid nanoparticles

J. Bader, P. Rüedi, V. Mantella, S. Geisshüsler, F. Brigger, B. M. Qureshi, J. Ortega Arroyo, E. Montanari, J.-C. Leroux

This paper develops a method to load nucleic acids into extracellular vesicles using sponge-like lipid nanoparticles, achieving 40% cargo loading and improved transfection efficiency.

bioRxiv · Apr 10, 2024Bioengineering

Functional whole genome screen of nutrient-starved Mycobacterium tuberculosis identifies genes involved in antibiotic tolerance

W. M. Matern, H. T. Harris, C. Danchik, M. McDonald, G. Patel, A. Srivastava, T. R. Ioerger, J. Bader, P. C. Karakousis

This study identifies Mtb genes involved in antibiotic tolerance under nutrient-starved conditions through a functional genome screen, revealing potential therapeutic targets.

bioRxiv · Apr 12, 2023 · PreprintMicrobiology

Genetic determinants of intrinsic antibiotic tolerance in Mycobacterium avium

W. M. Matern, H. Parker, C. Danchik, L. Hoover, J. Bader, P. C. Karakousis

This study identifies antibiotic tolerance genes in Mycobacterium avium through a genome-wide transposon screen, revealing potential targets for improving treatment of MAC infections.

bioRxiv · Feb 23, 2021Microbiology

Identifying the essential genes of Mycobacterium avium subsp. hominissuis with Tn-Seq using a rank-based filter procedure.

P. C. Karakousis, W. M. Matern, J. Bader, R. L. Jenquin

This study identifies essential genes in Mycobacterium avium subsp. hominissuis using Tn-Seq and a rank-based filter, finding 270 essential features overlapping with those in Mycobacterium tuberculosis.

bioRxiv · Jul 19, 2019Microbiology