J. Bielecki

Minimized Sample Consumption for Time-Resolved Serial Crystallography Applied to the Redox Cycle of Human NQO1

This paper demonstrates a method to reduce sample consumption in time-resolved serial crystallography by using segmented droplet generation and mix-and-inject approaches for studying NQO1's redox cycle.

Crystal structure of a bacterial photoactivated adenylate cyclase determined at room temperature by serial femtosecond crystallography

The paper determines the crystal structure of a bacterial photoactivated adenylate cyclase at room temperature using serial femtosecond crystallography and compares it with cryo structures to study structural changes upon light exposure.

Observation of a single protein by ultrafast X-ray diffraction

The paper demonstrates the first X-ray diffraction pattern from a single protein, Escherichia coli GroEL, showing the feasibility of ultrafast imaging of single proteins.

Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX

This paper determines the structure of Tpp49Aa1 using MHz-SFX and investigates its interaction with Cry48Aa1, expanding its known target range to include additional mosquito species.

Electrospray sample injection for single-particle imaging with X-ray lasers

This paper demonstrates an electrospray injector that reduces aerosol droplet size, enabling contaminant-free sample delivery for single-particle imaging with X-ray lasers.