Author

A. Grieco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:structural biology· 2 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. L. Pey· 2 shared J. M. Martin Garcia· 2 shared M. Medina· 2 shared A. Ansari· 1 shared A. Manna· 1 shared A. P. Mancuso· 1 shared A. Ros· 1 shared A. Round· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. L. Pey

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2 papers

Recent·Most cited

Minimized Sample Consumption for Time-Resolved Serial Crystallography Applied to the Redox Cycle of Human NQO1

D. Doppler, A. Grieco, D. Koh, A. Manna, A. Ansari, R. Alvarez, K. Karpos, H. Le, M. Sonker, G. Ketawala, S. Mahmud, I. Quereda Moraleda, A. L. Pey, R. Letrun, K. Doerner, , A. Ros

This paper demonstrates a method to reduce sample consumption in time-resolved serial crystallography by using segmented droplet generation and mix-and-inject approaches for studying NQO1's redox cycle.

bioRxiv · Apr 29, 2024Biochemistry

Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations

A. Grieco, S. Boneta, J. A. Gavira, A. L. Pey, S. Basu, J. Orlans, D. de Sanctis, M. Medina, J. M. Martin Garcia

This study determines the structure of hNQO1 with NADH using serial crystallography and simulations, showing NADH binding stabilizes the protein and drives functional cooperativity through structural communication.

Protein Science · Mar 19, 2024Peer-reviewedBiochemistry