Ionophore antibiotic X-206 is a potent and selective inhibitor of SARS-CoV-2 infection in vitro
E. B. Svenningsen, J. T. Jensen, J. Blay-Cadanet, H. Liu, S. Lin, J. M. Villameriel, D. Olagnier, M. Idorn, S. R. Paludan, C. K. Holm, T. B. Poulsen
This study identifies X-206, a polyether ionophore antibiotic, as a potent and selective inhibitor of SARS-CoV-2 infection in vitro with high selectivity and sub-nM efficacy.
bioRxiv · Jun 14, 2020Pharmacology & Toxicology