Author

J. Brezinova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Bileck· 1 shared A. Bolado· 1 shared A. Obr· 1 shared A. von Kriegsheim· 1 shared B. Collis· 1 shared C. Adrain· 1 shared C. Gerner· 1 shared D. Clancy· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Bileck

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Author profile →

2 papers

Recent·Most cited

Inhibition of Casein Kinase 2 induces cell death in chronic myelogenous leukemia cells resistant to tyrosine kinase inhibitors

O. Mitrovsky, D. Myslivcova, T. Machackova-Lopotova, A. Obr, K. Cermakova, S. Ransdorfova, J. Brezinova, H. Klamova, M. Zackova

This study shows that inhibiting Casein Kinase 2 (CK2) induces cell death in chronic myelogenous leukemia (CML) cells resistant to tyrosine kinase inhibitors (TKIs) and may enhance TKI efficacy.

bioRxiv · Jun 28, 2021Cancer Biology

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE

I. Oikonomidi, E. Burbridge, M. Cavadas, G. Sullivan, D. Clancy, B. Collis, J. Brezinova, J. Humpolickova, T. Hu, A. Bileck, C. Gerner, A. Bolado, A. von Kriegsheim, K. Strisovsky, S. J. Martin, C. Adrain

This study identifies iTAP as a novel iRhom interactor that stabilizes iRhom and TACE, essential for TNF secretion, and shows its role in regulating inflammation.

bioRxiv · Jan 30, 2018Biochemistry