Author

J. C. Hallam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Barwinska-Sendra· 1 shared A. J. Roe· 1 shared E. Oswald· 1 shared F. Vaz· 1 shared G. Douce· 1 shared J. A. Kirk· 1 shared J. Cole· 1 shared M. J. Ormsby· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Barwinska-Sendra

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2 papers

Recent·Most cited

An intact S-layer is advantageous to Clostridioides difficile within the host.

M. J. Ormsby, F. Vaz, J. A. Kirk, A. Barwinska-Sendra, J. C. Hallam, P. Lanzoni-Mangutchi, J. Cole, R. R. Chaudhuri, P. S. Salgado, R. P. Fagan, G. Douce

This paper shows that an intact S-layer in Clostridioides difficile enhances disease severity by analyzing revertants of an S-layer-null strain and their gene expression differences.

bioRxiv · Nov 22, 2022 · PreprintMicrobiology

The therapeutic potential of D-Serine in reducing expression of the cytopathic genotoxin colibactin

J. C. Hallam, N. O'Boyle, N. C. A. Turner, M. Tang-Fichaux, E. Oswald, A. J. Roe

This study shows D-Serine reduces colibactin expression and cytopathic effects in E. coli strains, suggesting its therapeutic potential for preventing colibactin-related diseases.

bioRxiv · Mar 8, 2022 · PreprintMicrobiology