Author

J. C. Iatridis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Hecht· 2 shared A. Lai· 2 shared D. Krishnamoorthy· 2 shared D. Laudier· 2 shared D. M. Natelson· 2 shared J. Gansau· 2 shared R. C. Hoy· 2 shared S. Illien-Junger· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

A. Hecht

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Author profile →

4 papers

Recent·Most cited

TNFR1-mediated senescence and lack of TNFR2-signaling limit human intervertebral disc cell repair in back pain conditions

J. Gansau, E. Grossi, L. Rodriguez, M. Wang, D. Laudier, S. Chaudhary, A. Hecht, W. Fu, R. Sebra, C. Liu, J. C. Iatridis

This study identifies TNFR1-mediated senescence and limited TNFR2 signaling as barriers to intervertebral disc cell repair in back pain, suggesting immunomodulation as a therapeutic strategy.

bioRxiv · Feb 22, 2024 · PreprintBioengineering

Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization-An In Vivo Rat Model

D. Wang, A. Lai, J. Gansau, A. Seifert, J. Munitz, K. Zaheer, N. Bhadouria, Y. Lee, P. Nasser, D. Laudier, N. Holguin, A. Hecht, J. C. Iatridis

bioRxiv · Jan 27, 2023Pathology

Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model

D. M. Natelson, A. Lai, D. Krishnamoorthy, R. C. Hoy, J. C. Iatridis, S. Illien-Junger

This study investigates sex-dependent effects of leptin receptor deficiency and Western diet on intervertebral disc pathology in a type 2 diabetes mouse model, finding altered disc morphology and bone quality in female mice.

bioRxiv · Dec 23, 2019Physiology

Dietary Advanced Glycation End-Product Consumption Leads to Mechanical Stiffening of Murine Intervertebral Discs

D. Krishnamoorthy, R. C. Hoy, D. M. Natelson, O. M. Torre, D. M. Laudier, J. C. Iatridis, S. Illien-Junger

This study shows that high dietary AGEs cause sex-specific structural and functional changes in mouse intervertebral discs, suggesting dietary interventions may help prevent disc degeneration, especially in diabetes.

bioRxiv · Jun 8, 2018Bioengineering