Author

E. Grossi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Amadoz· 1 shared A. Hecht· 1 shared C. Liu· 1 shared D. Laudier· 1 shared E. Goni· 1 shared F. P. Marchese· 1 shared J. C. Iatridis· 1 shared J. Gansau· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Amadoz

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Author profile →

2 papers

Recent·Most cited

TNFR1-mediated senescence and lack of TNFR2-signaling limit human intervertebral disc cell repair in back pain conditions

J. Gansau, E. Grossi, L. Rodriguez, M. Wang, D. Laudier, S. Chaudhary, A. Hecht, W. Fu, R. Sebra, C. Liu, J. C. Iatridis

This study identifies TNFR1-mediated senescence and limited TNFR2 signaling as barriers to intervertebral disc cell repair in back pain, suggesting immunomodulation as a therapeutic strategy.

bioRxiv · Feb 22, 2024 · PreprintBioengineering

A lncRNA-mediated metabolic rewiring of cell senescence

E. Grossi, F. P. Marchese, J. Gonzalez, E. Goni, J. M. Fernandez-Justel, A. Amadoz, N. Herranz, L. Puchades-Carrasco, M. Montes, M. Huarte

This study identifies sin-lncRNA, a long non-coding RNA that regulates mitochondrial metabolism during cellular senescence by modulating oxidative phosphorylation and DLST localization.

bioRxiv · Jan 25, 2024Cell Biology