Author

J. C. Regan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

L. Partridge· 2 shared Y.-X. Lu· 2 shared D. Kissler· 1 shared E. Funk· 1 shared E. Urena· 1 shared J. Fröhlich· 1 shared J. H. Catterson· 1 shared J. Lu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

L. Partridge

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Profound geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy

P. Juricic, Y.-X. Lu, T. Leech, L. F. Drews, J. Paulitz, J. Lu, T. Nespital, S. Azami, J. C. Regan, E. Funk, J. Fröhlich, S. Grönke, L. Partridge

Brief early adulthood rapamycin treatment in Drosophila and mice extends lifespan and maintains gut function through persistent intestinal autophagy and lysosomal enzyme levels.

bioRxiv · Apr 20, 2022Physiology

Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension

J. C. Regan, Y.-X. Lu, E. Urena, R. Meilenbrock, J. H. Catterson, D. Kissler, L. Partridge

This study shows that rapamycin extends lifespan in female Drosophila but not males, due to sex-specific autophagy regulation in intestinal enterocytes.

bioRxiv · Oct 22, 2021 · PreprintPhysiology