Profound geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
P. Juricic, Y.-X. Lu, T. Leech, L. F. Drews, J. Paulitz, J. Lu, T. Nespital, S. Azami, J. C. Regan, E. Funk, J. Fröhlich, S. Grönke, L. Partridge
Brief early adulthood rapamycin treatment in Drosophila and mice extends lifespan and maintains gut function through persistent intestinal autophagy and lysosomal enzyme levels.
bioRxiv · Apr 20, 2022Physiology