Author

J. C. Sang

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. Finley· 1 shared D. Klenerman· 1 shared F. Kundel· 1 shared R. Cliffe· 1 shared Y. Ye· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

D. Finley

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1 paper

Recent·Most cited

Filamentous aggregates are fragmented by the proteasome holoenzyme

R. Cliffe, J. C. Sang, F. Kundel, D. Finley, D. Klenerman, Y. Ye

This study shows the proteasome holoenzyme fragments amyloid fibrils into smaller, more toxic species, suggesting a novel degradation mechanism for filamentous aggregates.

bioRxiv · Nov 9, 2018Biophysics