Author

J. C. Sudar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Ballesteros· 1 shared C. Mulligan· 1 shared C. R. Nisler· 1 shared D. Sauer· 1 shared D.-N. Wang· 1 shared J. J. Marden· 1 shared J. M. Lotthammer· 1 shared J. Song· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. Ballesteros

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2 papers

Recent·Most cited

Structural basis of ion - substrate coupling in the Na+-dependent dicarboxylate transporter VcINDY

D. Sauer, J. J. Marden, J. C. Sudar, J. Song, C. Mulligan, D.-N. Wang

This study reveals the structural mechanism by which VcINDY couples sodium and substrate binding through an induced-fit mechanism, showing that sodium binding stabilizes the substrate binding site.

bioRxiv · Jan 11, 2022Biophysics

In Silico Electrophysiology of Inner-Ear Mechanotransduction Channel TMC1 Models

S. Walujkar, J. M. Lotthammer, C. R. Nisler, J. C. Sudar, A. Ballesteros, M. Sotomayor

The paper uses molecular dynamics simulations to study ion conduction in TMC1 models, revealing a peripheral permeation pathway and lipid-mediated gating mechanisms in inner-ear mechanotransduction channels.

bioRxiv · Sep 17, 2021 · PreprintBiophysics