Author

J. Chaires

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. O. Trent· 3 shared R. D. Gray· 2 shared D. Matulis· 1 shared L. Baranauskiene· 1 shared L. W. DeLeeuw· 1 shared R. C. Monsen· 1 shared R. del Villar-Guerra· 1 shared S. Arumugam· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

J. O. Trent

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

POT1 Stability and Binding Measured by Fluorescence Thermal Shift Assays

L. W. DeLeeuw, R. C. Monsen, V. Petrauskas, R. D. Gray, L. Baranauskiene, D. Matulis, J. O. Trent, J. Chaires

This paper describes two fluorescent thermal shift assays to quantify POT1 stability and DNA interactions, revealing mechanisms of POT1 inhibition.

bioRxiv · Jan 1, 2021Biophysics

Folding landscape of a parallel G-quadruplex

R. D. Gray, J. O. Trent, S. Arumugam, J. Chaires

The paper investigates the folding pathway of a G-quadruplex using spectroscopic and computational methods, revealing multiple intermediates and a slow unfolding process.

The Journal of Physical Chemistry Letters · Mar 7, 2019Peer-reviewedBiophysics

G-quadruplex secondary structure from circular dichroism spectroscopy

R. del Villar-Guerra, J. O. Trent, J. Chaires

This study builds a reference library of G-quadruplex CD spectra and develops an algorithm to estimate their secondary structure content using PCA and SVD.

bioRxiv · Sep 4, 2017Biophysics