Author

J. D. Zehr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. L. Kosakovsky Pond· 4 shared A. G. Lucaci· 3 shared L. B. Goodman· 3 shared D. P. Martin· 2 shared K. Ceres· 2 shared M. J. Stanhope· 2 shared A. Choi· 1 shared A. G. Ophir· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersEvolutionary Biology

S. L. Kosakovsky Pond

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Author profile →

5 papers

Recent·Most cited

HyphAeon: Attention on Evolution Across Deep Time Transforms Comparative Genomics

S. L. Kosakovsky Pond, S. Weaver, D. Callan, J. D. Zehr, A. G. Lucaci, H. Verdonk, A. Selberg, G. Brown, M. Chikina, N. L. Clark, K. D. Makova, D. P. Martin, A. Nekrutenko

HyphAeon is a transformer model that accelerates detection of episodic diversifying selection in mammalian genomes and enables new analytical capabilities beyond traditional dN/dS methods.

bioRxiv · Sep 10, 2026 · PreprintBioinformatics

Isolation of Actinomyces cricetomyis sp. nov from orocervicofacial abscesses of African giant pouched rats (Cricetomys ansorgei)

J. D. Zehr, R. J. Franklin-Guild, S. V. Nguyen, J. R. Petrone, R. N. Labitt, H. C. McQueary, S. Llanos-Soto, P. K. Mitchell, R. L. Tallmadge, A. G. Ophir, M. Jager, T. Wu, J. L. Jacobs, A. Thachil, B. Singh, L. B. Goodman

The paper isolates and characterizes a novel Actinomyces species from abscesses in African giant pouched rats.

bioRxiv · Apr 4, 2023 · PreprintMicrobiology

Natural selection differences detected in key protein domains between non-pathogenic and pathogenic Feline Coronavirus phenotypes

J. D. Zehr, S. L. Kosakovsky Pond, J. K. Millet, X. A. Olarte-Castillo, A. G. Lucaci, S. S. D, K. Ceres, A. Choi, G. Whittaker, L. B. Goodman, M. J. Stanhope

This study identifies natural selection differences in key protein domains between non-pathogenic FECV and pathogenic FIPV FCoVs, highlighting sites under positive selection associated with FIP development.

bioRxiv · Jan 11, 2023Evolutionary Biology

Human HspB1, HspB3, HspB5 and HspB8: Shaping these Disease Factors during Vertebrate Evolution

R. Benndorf, R. Velazquez, J. D. Zehr, S. L. Kosakovsky Pond, J. L. Martin, A. G. Lucaci

This study examines the evolutionary forces shaping four sHSPs (HspB1, HspB3, HspB5, HspB8) in vertebrates and links their selective pressures to disease-associated mutations.

bioRxiv · Feb 24, 2022Evolutionary Biology

Recent zoonotic spillover and tropism shift of a Canine Coronavirus is associated with relaxed selection and putative loss of function in NTD subdomain of spike protein.

J. D. Zehr, S. L. Kosakovsky Pond, D. P. Martin, K. Ceres, G. R. Whittaker, L. B. Goodman, M. J. Stanhope

This paper analyzes the evolutionary changes in the spike protein of a Canine Coronavirus isolate, identifying relaxed selection and amino acid substitutions associated with a shift in tropism from enteric to respiratory.

bioRxiv · Nov 15, 2021Evolutionary Biology