Author

J. L. Jacobs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

A. Kim· 3 shared J. W. Mellors· 3 shared M. D. Sobolewski· 3 shared W. Li· 3 shared Z. Sun· 3 shared A. M. Berezuk· 2 shared B. R. Treat· 2 shared C. Adams· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Kim

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Isolation of Actinomyces cricetomyis sp. nov from orocervicofacial abscesses of African giant pouched rats (Cricetomys ansorgei)

J. D. Zehr, R. J. Franklin-Guild, S. V. Nguyen, J. R. Petrone, R. N. Labitt, H. C. McQueary, S. Llanos-Soto, P. K. Mitchell, R. L. Tallmadge, A. G. Ophir, M. Jager, T. Wu, J. L. Jacobs, A. Thachil, B. Singh, L. B. Goodman

The paper isolates and characterizes a novel Actinomyces species from abscesses in African giant pouched rats.

bioRxiv · Apr 4, 2023 · PreprintMicrobiology

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

C. Chen, J. W. Saville, M. M. Marti, A. Schaefer, M. H. Cheng, D. Mannar, X. Zhu, A. M. Berezuk, A. Banerjee, M. D. Sobolewski, A. Kim, B. R. Treat, P. M. Da Silva Castanha, N. Enick, K. D. McCormick, , W. Li

This study identifies a biparatopic VH domain that neutralizes SARS-CoV-2 VOCs, including Omicron, with high potency in vitro and in a mouse model.

bioRxiv · Feb 18, 2022 · PreprintImmunology

Emerging SARS-CoV-2 Variants of Concern: Spike Protein Mutational Analysis and Epitope for Broad Neutralization

D. Mannar, J. W. Saville, Z. Sun, X. Zhu, M. M. Marti, S. S. Srivastava, A. M. Berezuk, S. Zhou, K. Tuttle, M. D. Sobolewski, A. Kim, B. R. Treat, P. Mayrelle Da Silva Castanha, J. L. Jacobs, S. M. Barratt-Boyes, , S. Subramaniam

This study identifies a broadly neutralizing antibody fragment and analyzes spike protein mutations in SARS-CoV-2 variants to understand their structural and functional impacts on antibody evasion.

bioRxiv · Dec 17, 2021Biochemistry

Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains

Z. Sun, A. Kim, M. D. Sobolewski, N. Enick, C. Chen, C. Adams, J. L. Jacobs, K. D. McCormick, J. W. Mellors, D. S. Dimitrov, W. Li

The paper evaluates an antibody domain's ability to neutralize SARS-CoV-2 variants with mutations in the RBD, showing it neutralizes the triple mutation variant but not others.

bioRxiv · Mar 22, 2021 · PreprintImmunology