Author

R. Velazquez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. C. Palmer· 1 shared A. G. Lucaci· 1 shared A. Green· 1 shared A. Loo· 1 shared A. Malamas· 1 shared A. Synan· 1 shared C. Bullock· 1 shared C. Kowal· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. C. Palmer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor specificity

A. Synan, N. C. Wu, R. Velazquez, C. Logel, K. Mueller, A. Green, P. Barzaghi-Rinaudo, Q. Simmons, S. Mercan, X. Shi, J. Korn, M. McLaughlin, W. R. Tschantz, D. Hainzl, A. Malamas, , J. A. D'Alessio

This study develops a bispecific antibody-drug conjugate targeting pCAD and CDH17, showing antitumor activity in dual antigen-expressing tumors but not in single antigen-expressing tumors.

bioRxiv · Apr 19, 2024Cancer Biology

Low circulating choline, a modifiable dietary factor, is associated with the pathological progression and metabolome dysfunction in Alzheimers disease.

J. M. Judd, P. Jasbi, W. Winslow, G. E. Serrano, J. Klein-Seetharaman, T. Beach, R. Velazquez

The paper investigates the association between low circulating choline and Alzheimer's disease progression, finding it linked to neuropathological features and metabolome dysfunction.

bioRxiv · May 6, 2023Pathology

Human HspB1, HspB3, HspB5 and HspB8: Shaping these Disease Factors during Vertebrate Evolution

R. Benndorf, R. Velazquez, J. D. Zehr, S. L. Kosakovsky Pond, J. L. Martin, A. G. Lucaci

This study examines the evolutionary forces shaping four sHSPs (HspB1, HspB3, HspB5, HspB8) in vertebrates and links their selective pressures to disease-associated mutations.

bioRxiv · Feb 24, 2022Evolutionary Biology

Biomarker-guided treatment strategies for ovarian cancer identified from a heterogeneous panel of patient-derived tumor xenografts

A. C. Palmer, D. Plana, H. Gao, J. M. Korn, G. Yang, J. Green, X. Zhang, R. Velazquez, M. E. McLaughlin, D. A. Ruddy, C. Kowal, J. Goldovitz, C. Bullock, S. Rivera, D. Rakiec, , J. A. Williams

This study identifies biomarker-guided treatment strategies for ovarian cancer using patient-derived tumor xenografts, finding that nearly 90% of PDXs responded to at least one targeted therapy.

bioRxiv · Jan 8, 2020Cancer Biology