Author

J. Drnevich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:behavioral assay· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Jamal· 1 shared A. N. Mogol· 1 shared A. S. Casiano· 1 shared A. S. Raghavendra· 1 shared B. H. Park· 1 shared B. Herb· 1 shared B. Link· 1 shared B. S. Katzenellenbogen· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPhysiology

A. Jamal

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Author profile →

5 papers

Recent·Most cited

Myofibroblast Ccn3 is regulated by Yap and Wwtr1 and contributes to adverse cardiac outcomes

M. Flinn, S. Alvarez-Argote, M. C. Knas, V. Alencar, S. J. Paddock, X. Zhou, T. Buddell, A. Jamal, P. Liu, J. Drnevich, M. Patterson, B. Link, C. C. O'Meara

This study shows that Yap and Wwtr1 regulate Ccn3 in cardiac myofibroblasts, and their depletion reduces fibrosis and improves cardiac function after myocardial infarction.

bioRxiv · Dec 1, 2022Physiology

Mevalonate metabolites contribute to granulocyte chemotaxis and mortality in murine endotoxemia

J. Hussain, C. G. Ousley, S. A. Krauklis, E. L. Dray, J. Drnevich, K. Justyna, M. D. Distefano, D. B. McKim

This study shows that statin pretreatment improves survival in murine endotoxemia by reducing granulocyte chemotaxis through geranylgeranylation inhibition.

bioRxiv · Sep 13, 2022 · PreprintImmunology

Targeting metabolic adaptations in the breast cancer liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

Q. Zuo, A. N. Mogol, Y.-J. Liu, A. S. Casiano, C. Chien, J. Drnevich, O. B. Imir, E. Kulkoyluoglu-Cotul, N. H. Park, D. J. Shapiro, B. H. Park, Y. Ziegler, B. S. Katzenellenbogen, E. Aranda, J. D. O'Neill, , Z. Madak-Erdogan

This study identifies a mechanism of endocrine resistance in liver metastases of ER+ breast cancer and shows that a fasting-mimicking diet enhances the efficacy of fulvestrant treatment.

bioRxiv · Sep 7, 2021Cancer Biology

The evolution of extreme fertility defied ancestral gonadotropin mediated brain-reproduction tradeoff

H. Y. Shpigler, B. Herb, J. Drnevich, M. Band, G. E. Robinson, G. Bloch

The paper investigates JH's role in bumble bees, finding it upregulates metabolic genes in the fat body and downregulates protein turnover in the brain, suggesting a tradeoff between fertility and brain health.

bioRxiv · Apr 30, 2020 · PreprintEvolutionary Biology

A common pattern of influenza A virus single cell gene expression heterogeneity governs the innate antiviral response to infection

J. C. Vera, J. Sun, Y. T. Lin, J. Drnevich, R. Ke, C. B. Brooke

This study identifies a common pattern of viral gene expression heterogeneity in influenza A virus that influences host antiviral responses across subtypes.

bioRxiv · Dec 10, 2019Microbiology