Author

J. E. Endress

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

I. S. Harris· 2 shared A. C. Wang· 1 shared A. Janzer· 1 shared A. Novikova· 1 shared A. Sutter· 1 shared A. Tebeje· 1 shared B. Huang· 1 shared C. E. Bird· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

I. S. Harris

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2 papers

Recent·Most cited

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

V. Rawat, P. DeLear, P. Prashanth, M. E. Ozgurses, A. Tebeje, P. A. Burns, K. O. Conger, C. Solis, Y. Hasnain, A. Novikova, J. E. Endress, P. Gonzalez-Sanchez, W. Dong, G. Stephanopoulos, G. M. DeNicola, , J. L. Coloff

The paper screens drugs in human physiologic medium and identifies uric acid as an inhibitor of rigosertib's efficacy.

bioRxiv · Jul 26, 2023Cancer Biology

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

D. D. Shi, M. R. Savani, M. M. Levitt, A. C. Wang, J. E. Endress, C. E. Bird, J. Buehler, S. A. Stopka, M. S. Regan, Y.-F. Lin, W. Gao, J. Khanal, M. Xu, B. Huang, R. B. Jennings, , McBray

This study identifies de novo pyrimidine synthesis as a therapeutic target in IDH mutant gliomas, showing that DHODH inhibitors are effective in preclinical models.

bioRxiv · Nov 30, 2021Cancer Biology