Author

D. D. Shi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

K. G. Abdullah· 2 shared L. C. Gattie· 2 shared L. G. Zacharias· 2 shared M. R. Savani· 2 shared M. S. Martin-Sandoval· 2 shared R. J. DeBerardinis· 2 shared T. E. Richardson· 2 shared T. P. Mathews· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

K. G. Abdullah

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment

M. R. Savani, M. El Shami, L. C. Gattie, B. C. Smith, W. H. Hicks, S. S. Oken, L. G. Zacharias, M. S. Martin-Sandoval, E. Y. Montgomery, Y. Xiao, D. D. Shi, J. N. Rich, T. E. Richardson, P. O. Zinn, B. C. Lega, , K. G. Abdullah

This paper develops an in vitro method using human plasma-like medium to study glioma metabolism and immune interactions, revealing microenvironment-dependent metabolic features and immune responses.

bioRxiv · May 29, 2023Cancer Biology

The vascularised chamber device significantly enhances the survival of transplanted liver organoids

D. D. Shi, E. Makris, Y.-W. Gerrand, P.-H. Lo, G. C. Yeoh, W. A. Morrison, G. M. Mitchell, K. K. Yap

This study shows that transplanting liver organoids into a vascularised chamber device significantly improves their survival compared to other sites and methods.

bioRxiv · Apr 24, 2023 · PreprintBioengineering

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

D. D. Shi, M. R. Savani, M. M. Levitt, A. C. Wang, J. E. Endress, C. E. Bird, J. Buehler, S. A. Stopka, M. S. Regan, Y.-F. Lin, W. Gao, J. Khanal, M. Xu, B. Huang, R. B. Jennings, , McBray

This study identifies de novo pyrimidine synthesis as a therapeutic target in IDH mutant gliomas, showing that DHODH inhibitors are effective in preclinical models.

bioRxiv · Nov 30, 2021Cancer Biology