Author

J. Arreola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. J. De Jesus-Perez· 2 shared A. Gopalkrishnan· 1 shared A. Yassin-Kassab· 1 shared C. A. Bertrand· 1 shared D. Umamaheswar· 1 shared G. A. Mendez-Maldonado· 1 shared G. R. Hammond· 1 shared I. L. Gonzalez-Hernandez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

J. J. De Jesus-Perez

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Author profile →

2 papers

Recent·Most cited

Missense mutations in the calcium-activated chloride channel TMEM16A promote tumor growth by activating oncogenic signaling in Human Cancer.

S. Cruz-Rangel, J. J. De Jesus-Perez, A. Gopalkrishnan, R. Gomez-Casal, J. Pacheco, M. R. Brown, A. Yassin-Kassab, G. R. Hammond, C. A. Bertrand, J. Arreola, K. Kiselyov, D. Umamaheswar

This paper investigates TMEM16A missense mutations in cancer, finding they promote tumor growth through altered signaling, independent of chloride flux.

bioRxiv · Jun 21, 2023 · PreprintCancer Biology

ELECTRO-STERIC MECHANISM OF CLC-2 CHLORIDE CHANNEL ACTIVATION

J. J. De Jesus-Perez, G. A. Mendez-Maldonado, I. L. Gonzalez-Hernandez, V. De la Rosa, R. Gastelum-Garibaldi, J. E. Sanchez-Rodriguez, J. Arreola

This study identifies the electro-steric mechanism of CLC-2 chloride channel activation through homology modeling, molecular dynamics simulations, and functional experiments.

bioRxiv · Jun 12, 2020 · PreprintPhysiology