Author

J. Einsiedel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. L. Kaplan· 1 shared B. K. Shoichet· 1 shared F. Liu· 1 shared H. L. Pietz· 1 shared I. S. Kondratov· 1 shared J. Chen· 1 shared J. J. Irwin· 1 shared J. Levring· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. L. Kaplan

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1 paper

Recent·Most cited

Structure-based discovery of CFTR potentiators and inhibitors

F. Liu, A. L. Kaplan, J. Levring, J. Einsiedel, S. Tiedt, K. Distler, N. Omattage, I. S. Kondratov, Y. S. Moroz, H. L. Pietz, J. J. Irwin, P. Gmeiner, B. K. Shoichet, J. Chen

The paper identifies novel CFTR modulators using molecular docking, electrophysiology, cryo-EM, and medicinal chemistry, discovering potentiators and inhibitors with mid-nanomolar activity.

bioRxiv · Sep 9, 2023Biophysics