Author

S. Tiedt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

A. D. zu Senden· 1 shared A. J. Janjic· 1 shared A. L. Kaplan· 1 shared A. Leunig· 1 shared A. Martinez-Navarro· 1 shared B. Engelmann· 1 shared B. K. Shoichet· 1 shared B. Kilani· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. D. zu Senden

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis

K. Pekayvaz, M. Joppich, S. Brambs, V. Knottenberg, L. Eivers, A. Martinez-Navarro, R. Kaiser, N. Meissner, B. Kilani, S. Stockhausen, A. J. Janjic, V. Polewka, F. W. Wendler, A. D. zu Senden, A. Leunig, , K. Stark

The paper maps immune cell trajectories and interactions in human thrombi, identifying prothrombotic and thrombolytic monocyte and neutrophil subsets with therapeutic implications.

bioRxiv · Jan 10, 2024 · PreprintImmunology

Structure-based discovery of CFTR potentiators and inhibitors

F. Liu, A. L. Kaplan, J. Levring, J. Einsiedel, S. Tiedt, K. Distler, N. Omattage, I. S. Kondratov, Y. S. Moroz, H. L. Pietz, J. J. Irwin, P. Gmeiner, B. K. Shoichet, J. Chen

The paper identifies novel CFTR modulators using molecular docking, electrophysiology, cryo-EM, and medicinal chemistry, discovering potentiators and inhibitors with mid-nanomolar activity.

bioRxiv · Sep 9, 2023Biophysics