BiophysicsbioRxiv
Structural insight into the stabilization of microtubules by taxanes
A. E. Prota, D. Lucena-Agell, Y. Ma…·J. F. Diaz
This study determines the crystal structures of taxane-tubulin complexes and uses simulations to elucidate how taxanes stabilize microtubules through conformational changes and ligand binding.
DOI 10.7554/elife.84791