Author

J. F. Loome

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Schaefer· 2 shared E. Anderson· 2 shared K. L. Gully· 2 shared M. R. Zweigart· 2 shared M. T. Heise· 2 shared R. S. Baric· 2 shared S. R. Leist· 2 shared V. Baxter· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Schaefer

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2 papers

Recent·Most cited

Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination

L. E. Adams, S. R. Leist, K. H. Dinnon, A. West, K. L. Gully, E. Anderson, J. F. Loome, E. Madden, J. Powers, A. Schaefer, S. Sarkar, I. Castillo, J. Maron, R. P. McNamara, H. L. Bertera, , R. S. Baric

This study shows that non-neutralizing antibodies targeting FcR4 and spike S2 provide cross-protection against sarbecoviruses after alphavirus vector vaccination.

bioRxiv · Nov 28, 2022Microbiology

A Multitrait Locus Regulates Sarbecovirus Pathogenesis

R. S. Baric, A. Schaefer, S. R. Leist, L. Gralinski, D. Martinez, E. S. Winkler, K. Okuda, P. E. Hawkins, K. L. Gully, R. L. Graham, T. D. Scobey, T. A. Bell, P. Hock, G. D. Shaw, J. F. Loome, , M. T. Ferris

The paper identifies a multitrait locus on mouse Chromosome 9 that regulates SARS-CoV, SARS-CoV-2, and bat sarbecovirus disease severity, with candidate genes CCR9 and CXCR6.

bioRxiv · Jun 1, 2022Microbiology