Author

J. Farnung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. E. Corn· 2 shared J. W. Bode· 2 shared M. Muhar· 2 shared J. R. Liang· 1 shared K. A. Tolmachova· 1 shared M. Cernakova· 1 shared N. D. Sidiropoulos· 1 shared R. Hofmann· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

J. E. Corn

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2 papers

Recent·Most cited

C-terminal amides mark proteins for degradation via SCF/FBXO31

M. Muhar, J. Farnung, R. Hofmann, M. Cernakova, N. D. Sidiropoulos, J. W. Bode, J. E. Corn

The paper identifies C-terminal amides as signals for protein degradation via SCF/FBXO31, showing that oxidative stress generates these marks and a mutation disrupts this process, leading to toxicity.

bioRxiv · Jun 29, 2023Cell Biology

Human ATG3 contains a non-canonical LIR motif crucial for its enzymatic activity in autophagy

J. Farnung, M. Muhar, J. R. Liang, K. A. Tolmachova, R. M. Benoit, J. E. Corn, J. W. Bode

The paper identifies a non-canonical LIR motif in ATG3 essential for its enzymatic activity in autophagy, showing its role in LC3 lipidation and thioester formation.

bioRxiv · Aug 2, 2022 · PreprintBiochemistry