Author

J. R. Liang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Lingeman· 2 shared J. E. Corn· 2 shared S. Ahmed· 2 shared J. Corn· 1 shared J. Farnung· 1 shared J. Olzmann· 1 shared J. W. Bode· 1 shared K. A. Tolmachova· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

E. Lingeman

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Author profile →

3 papers

Recent·Most cited

Human ATG3 contains a non-canonical LIR motif crucial for its enzymatic activity in autophagy

J. Farnung, M. Muhar, J. R. Liang, K. A. Tolmachova, R. M. Benoit, J. E. Corn, J. W. Bode

The paper identifies a non-canonical LIR motif in ATG3 essential for its enzymatic activity in autophagy, showing its role in LC3 lipidation and thioester formation.

bioRxiv · Aug 2, 2022 · PreprintBiochemistry

A genome-wide screen for ER autophagy highlights key roles of mitochondrial metabolism and ER- resident UFMylation

J. R. Liang, E. Lingeman, T. Luong, S. Ahmed, T. Nguyen, J. Olzmann, J. E. Corn

The paper identifies 200 factors involved in human ER-phagy through CRISPRi screening and reveals mitochondrial metabolism and ER-resident UFMylation as key regulators.

bioRxiv · Feb 25, 2019Cell Biology

Atlastins mediate selective autophagy of the endoplasmic reticulum

J. R. Liang, E. Lingeman, S. Ahmed, J. Corn

This study identifies Atlastins as key regulators of ER-phagy, showing they facilitate ER membrane remodeling for autophagosomal engulfment and linking their dysfunction to hereditary spastic paraplegia.

bioRxiv · Mar 3, 2018Cell Biology