Microvasculopathy And Soft Tissue Calcification In Mice Are Governed by Fetuin-A, Pyrophosphate And Magnesium
A. Babler, C. Schmitz, A. Buescher, M. Herrmann, F. Gremse, T. G. Gorgels, J. Floege, W. Jahnen-Dechent
The paper identifies fetuin-A, pyrophosphate, and magnesium as key regulators of calcification in fetuin-A deficient mice and shows that their combined deficiency can be mitigated by dietary or parenteral supplementation.
bioRxiv · Oct 1, 2019Physiology