ASCT2 is the primary serine transporter in cancer cells
K. O. Conger, C. Chidley, M. E. Ozgurses, H. Zhao, Y. Kim, S. E. Semina, P. A. Burns, V. Rawat, R. Sheldon, I. Ben-Sahra, J. Frasor, P. K. Sorger, G. M. DeNicola, J. L. Coloff
This study identifies ASCT2 as the primary serine transporter in cancer cells and shows its role in purine biosynthesis and therapeutic targeting.
bioRxiv · Oct 9, 2023 · PreprintCancer Biology