Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
K. O. Conger, C. Chidley, M. E. Ozgurses, H. Zhao, Y. Kim, S. E. Semina, P. A. Burns, V. Rawat, R. Sheldon, I. Ben-Sahra, J. Frasor, P. K. Sorger, G. M. DeNicola, J. L. Coloff
This study identifies ASCT2 as the primary serine transporter in cancer cells and shows its role in purine biosynthesis and therapeutic targeting.
bioRxiv · Oct 9, 2023 · PreprintCancer Biology
C. Chidley, A. M. Darnell, B. L. Gaudio, E. C. Lien, A. M. Barbeau, M. G. Vander Heiden, P. K. Sorger
This study uses a CRISPRi/a screening platform to identify nutrient transporters critical for cancer cell proliferation in diverse microenvironments and reveals their functional roles.
bioRxiv · Jan 26, 2023Cancer Biology
B. T. Do, P. P. Hsu, S. Y. Vermeulen, Z. Wang, T. Hirz, K. L. Abbott, N. Aziz, J. M. Replogle, S. Bjelosevic, J. Paolino, S. Nelson, S. Block, A. M. Darnell, R. Ferreira, H. Zhang, , M. G. Vander Heiden
The paper shows that nucleotide depletion and DNA replication stress drive cell fate transitions in hematopoietic systems by activating lineage-specific maturation genes.
bioRxiv · Aug 16, 2022Cancer Biology
L. Gerosa, C. Chidley, F. Froehlich, G. Sanchez, S. K. Lim, J. Muhlich, J.-Y. Chen, G. J. Baker, D. Schapiro, T. Shi, L. Yi, C. D. Nicora, A. Claas, D. A. Lauffenburger, W.-J. Qian, , P. K. Sorger
The paper shows that sporadic ERK pulses in BRAFV600E melanoma cells drive non-genetic resistance to RAF/MEK inhibitors.
bioRxiv · Sep 8, 2019Cancer Biology
A. C. Palmer, C. Chidley, P. K. Sorger
This study analyzes the R-CHOP combination therapy for lymphomas, finding low cross-resistance and drug additivity rather than synergy contribute to its effectiveness.
bioRxiv · Jul 12, 2019Cancer Biology